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. 2022 Aug 24;13(9):1511. doi: 10.3390/genes13091511

Table 3.

Known genes associated with a stripe pattern of RIR chicks in GWAS.

Association Genes Position (bp) Full Name Biological Functions
KITLG GGA1 43015486–43066975 KIT ligand Melanoblasts/melanocytes proliferation, differentiation, migration, colonization, melanin production, gametogenesis, and hematopoiesis [32,33,34,35,36,37].
TMTC3 GGA1 42888363–42945679 Transmembrane and tetratricopeptide repeat containing 3 Cellular adherence, cell migration, and embryogenesis [45,46].
TSPAN19 GGA1 41773256–41785441 Tetraspanin 19 Plasma inhibin B levels [47].
ALX1 GGA1 41898277–41919541 ALX homeobox 1 Effect craniofacial development and related to beak shape in Darwin’s finches [48].
RASSF9 GGA1 42160804–42190042 Ras association domain family member 9 Regulating tumor proliferation and maintainepidermal homeostasis [49,50,51].
NTS GGA1 42207171–42220099 Neurotensin Regulatory of the central nervous system and digestive system, and promoting tumor metastasis, etc. [52].
MGAT4C GGA1 42251047–42358204 MGAT4 family member C Related to animal growth traits [53,54].
C12orf50 GGA1 42813465–42822840 C12orf50 homolog Unclear
C12orf29 GGA1 42829927–42836694 C12orf29 homolog Skeletal biology [55].