Figure 3.
The main effects and mechanisms of SCFAs on obesity. ↓ represents decrease, and ↑ represents increase. Abbreviation: Acc1, acetyl-CoA carboxylase-1; BAT, brown adipose tissue; CD137, tumor necrosis factor receptor superfamily member 9; COX IV, cytochrome-C oxidase IV; CPT, carnitine palmitoyl transferase; FAS, fatty acid synthase; FFAR2, free fatty acid receptor 2; GLP-1, glucagon-like peptide 1; LIPE, lipase hormone sensitive; NTS, nucleus tractus solitaries; PYY, peptide YY; SCFA, short-chain fatty acid; SREBP-1C, sterol-regulatory element-binding protein 1C; Tfam, mitochondrial transcription factor A; TFPα, trifunctional protein alpha; WAT, white adipose tissue.
