Table 1.

Details of all datasets used in this study.

Data Description	Data Location	Reference
Horvath ageing clock	Publication suppl. data	Horvath (2013) [19]
Levine ageing clock	Publication suppl. Data	Levine et al. (2018) [24]
Stubbs ageing clock	GEO: GSE93957/publication suppl. Data	Stubbs et al. (2017) [25]
Meer ageing clock	GEO: GSE121141/publication suppl. Data)	Meer et al. (2018) [26]
Petkovich ageing clock	GEO: GSE80672/publication suppl. Data)	Petkovich et al. (2017) [27]
Human G4-seq (K+)	GEO: GSM3003539	Marsico et al. (2019) [8]
Mice G4-seq (K+)	GEO: GSM3003547	Marsico et al. (2019) [8]
TET1 (mouse ESCs) ChIP-Seq	GEO: GSE24841	Williams et al. (2011) [25]
TET2 (mouse ESCs) ChIP-seq	GEO: GSE41720	Chen et al. (2013) [26]
TET1 (human ESCs) ChIP-seq	GEO: GSE99346	Verma et al. (2018) [27]
DNMT1 (K562) ChIP-seq	GEO: GSE92213	ENCODE [28]
DNMT1 (HepG2) ChIP-seq	GEO: GSE170872	ENCODE [28]
DNMT3b (HepG2) ChIP-seq	GEO: GSE95953	ENCODE [28]
NHEK BG4-ChIP	GEO: GSE76688	Hänsel-Hertsch et al. (2016) [9]
HaCaT BG4-ChIP	GEO: GSE76688	Hänsel-Hertsch et al. (2016) [9]
K562 BG4-ChIP	GEO: GSE107690	Mao et al. (2018) [15]