Figure 2.

Unrooted phylogenetic tree revealing the four main clusters formed by CRY/PL family members. The 6-4 photolyase cluster (I) includes the mammalian type MCRY (red), the Drosophila-type DCRY (blue), CRY4 involved in magnetoreception (purple) and the 6-4 photolyase itself (pink). The CPDII cluster (II) consists of CPDII photolyases (light green). The CPDI/III cluster (III) includes the CPDI (dark brown) & CPDIII photolyase (light brown), the plant cryptochrome PCRY (dark green), and the PCRY-like (turquoise). The DASH cluster (IV) consists of DASH-CRY (orange) and the plant photolyase PPL (yellow). Branches we could not precisely assign are shown in grey.