Table 1.
Application | Hydrogel Polymer System | Payload | Ultrasound Parameters | Reference |
---|---|---|---|---|
Bone Regeneration |
Alginate Hydrogel |
BMP-2 | 2.5 min/h for 5 h Amplitude of 25% 9.6 mW/cm2 |
[106] |
Cartilage Repair | Chitosan Hydrogel |
BMSCs aided by nanocarriers | 1 MHz 2–3 W/cm2 20–30% duty cycle |
[72] |
Bone Regeneration |
Alginate Hydrogel |
BMP-2 conjugated gold nanoparticles | 2.5 min/h for 5 h Amplitude of 25% 9.6 mW/cm2 |
[93] |
Cartilage Repair |
Chitosan Hydrogel |
Kartogenin on microparticles |
2 and 5 min intervals | [115] |
Skin Repair | Cellulose Hydrogel Film |
Mimosa drug | LIFU 23, 43, and 96 kHz 5–30 W |
[116] |
Vascularization | Fibrin Hydrogel | bFGF release | 100 Hz, 6.1 MPa 5.4 μs pulse |
[117] |
Bone Regeneration |
Collagen Hydrogel |
Osteoblasts | LIPUS 1 MHz, 1 kHz, 1 Hz Duty cycle: 20%, 50% or 100% 30 and 150 mW/cm2 |
[65] |