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Micronuclei vs. CTCAE grades. The number of spontaneous micronuclei per 100 cells (A) or micronuclei assessed 24 h post-irradiation per 100 cells (B) from 200 COPERNIC cell lines were plotted against the corresponding CTCAE grade values (closed circles). Each point corresponds to the mean ± standard error of the mean (SEM) of three independent triplicates, at least. The points corresponding to the ATM- (open circles) and the LIG4- (open triangles) mutated cell lines are indicated.
