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. 2022 Sep 6;23(18):10266. doi: 10.3390/ijms231810266

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Representative images of H&E-stained left ventricle in longitudinal sections in Normal, OB (Obese control), and OB + OR (obese and orlistat 10 mg/kg/day) groups (magnification ×400, scale bar = 50 μm). Normal group revealed a normal architecture of cardiomyocyte cells which were lined in homogenous pattern. The OB and OB + OR groups exhibited significant increases of cardiomyocyte diameter when compared to Normal group in conjunction with high infiltration of inflammatory cells in OB group (yellow arrow). ^a p < 0.05 compared with Normal group. Data were analyzed by One-way ANOVA followed by Tukey’s post-hoc test.