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. 2022 Sep 7;23(18):10319. doi: 10.3390/ijms231810319

Figure 9.

Figure 9

Compound (1s) delays cell cycle progression in a time- and dose-dependent manner. Cells were grown for (a,c–e) 48 h or (b,f–h) 72 h without (CTRL) or in the presence of (1s). Cell cycle phase population (G0/1; S; G2/M) was determined based on the signal of the PI-DNA complex using CytExpert. (a,b) Columns represent the mean (n = 3). Statistical difference was calculated using two-way ANOVA vs. CTRL (** p < 0.01, *** p < 0.001). (b–h) Representative histograms depicting the cell count within the PI-signal were illustrated with CytExpert.