Table 6.
Flow cytometric analysis of platelet receptor expression and oxidative stress in LVAD patients with and without NSB prior LVAD implantation.
| Parameter | Bleeders (n = 18) |
Non-Bleeders (n = 18) |
p-Value |
|---|---|---|---|
| % P-selectin+ platelets | 7.2 ± 2.6 | 12.4 ± 8.1 | 0.02 |
| % GP1bα+ platelets | 88.4 ± 25.5 | 93.4 ± 14.2 | 0.47 |
| % CD63+ platelets | 0.57 ± 0.32 | 3.29 ± 6.14 | 0.08 |
| % GPIIb/IIIa+ platelets | 77.8 ± 42.7 | 94.5 ± 23.6 | 0.16 |
| % DHR123+ platelets | 88.4 ± 9.6 | 84.4 ± 7.7 | 0.17 |
| % MitoTracker Green+ platelets | 30.0 ± 25.2 | 23.5 ± 13.9 | 0.34 |
| MFI P-selectin+ platelets | 1227 ± 354 | 1330 ± 463 | 0.46 |
| MFI GP1bα+ platelets | 930 ± 807 | 674 ± 257 | 0.21 |
| MFI CD63+ platelets | 1544 ± 1169 | 2727 ± 3020 | 0.14 |
| MFI GPIIb/IIIa+ platelets | 26,900 ± 13,608 | 36,259 ± 9913 | 0.02 |
| MFI DHR123+ platelets | 742 ± 435 | 575 ± 285 | 0.18 |
CD, cluster of differentiation; DHR123, dihydrorhodamine123; GP, glycoprotein; MFI, mean fluorescence intensity; NSB, non-surgical bleeding.