Figure 3.

Sankey diagram demonstrating the reclassification of patients after genetic analysis. The left column shows the clinical classification prior to genetic analysis. The right column reflects the clinical classification after reclassification. PAH (pulmonary arterial hypertension); PAH-CHD (pulmonary arterial hypertension associated with congenital heart disease); PVOD (pulmonary veno-occlusive disease). The size of each section represents the number of subjects in each classification; for example, the number of subjects classified with IPAH was lower after reclassification according to genetic testing results.