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. 2022 Sep 9;13:969924. doi: 10.3389/fendo.2022.969924

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Copyright © 2022 López-Soldado, Guinovart and Duran

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of lipogenic genes is unaltered in db/db-PTG mice (A) Hepatic TAG content, (B) Hepatic ACC1 mRNA expression, (C) Hepatic FAS mRNA expression, (D) Hepatic SCD1 mRNA expression, and (E) Hepatic GPAT1 mRNA expression of db/db and db/db-PTG mice, and non-diabetic controls (n=6-12 in all experiments). All values are mean ± SEM. **P<0.01, ***P<0.001. For figure (A) Diabetes factor (F ratio=219.5, P<0.0001), PTG factor (F ratio=1.638, P=0.2095), Interaction (F ratio=0.8095, P=0.3748). For figure (B) Diabetes factor (F ratio=73.11, P<0.0001), PTG factor (F ratio=0.7406, P=0.3992), Interaction (F ratio=0.2758, P=0.6050). For figure (C) Diabetes factor (F ratio=26.50, P<0.0001), PTG factor (F ratio=1.910, P=0.1815), Interaction (F ratio=0.4528, P=0.5083). For figure (D) Diabetes factor (F ratio=46.03, P<0.0001), PTG factor (F ratio=1.592, P=0.2216), Interaction (F ratio=0.2301, P=0.6367). For figure (E) Diabetes factor (F ratio=55.54, P<0.0001), PTG factor (F ratio=0.8379, P=0.374), Interaction (F ratio=2.910, P=0.1028).