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. 2022 Sep 9;13:944991. doi: 10.3389/fendo.2022.944991

Table 5.

Ten-year CVD risk reflected by FRS among different levels of multiple inflammation indicators.

Ten-year CVD risk
Men >10%/women >11% Men >20%/women >22% Both >30%
N % N % N %
MHR
 T1 632 25.7 156 6.4 22 0.9
 T2 757 31.1 202 8.3 31 1.3
 T3 1017 40.1 399 15.7 90 3.6
 p for trend <0.001 <0.001 <0.001
NLR
 T1 682 27.9 198 8.1 32 1.3
 T2 820 32.7 246 9.8 44 1.8
 T3 904 36.6 313 12.7 67 2.7
 p for trend <0.001 <0.001 <0.001
SII
 T1 782 31.6 232 9.4 36 1.5
 T2 784 31.7 254 10.3 55 2.2
 T3 840 34.0 321 13.0 79 3.2
 p for trend 0.007 0.025 <0.001
SIRI
 T1 597 24.2 156 6.3 21 0.9
 T2 848 33.0 242 9.4 48 1.9
 T3 961 40.4 359 15.1 74 3.1
 p for trend <0.001 <0.001 <0.001

The detailed intervals of these indicators were as the following: (1) MHR, T1: ≤0.27; T2: 0.28–0.42; T3: ≥0.43; (2) NLR, T1: ≤1.47; T2: 1.48–2.08; T3: ≥2.09; (3) SII, T1: ≤282.63; T2: 282.64–427.34; T3: ≥427.38; (4) SIRI, T1: ≤0.61; T2: 0.62–1.03; T3: ≥1.04. CVD, cardiovascular disease; FRS, Framingham risk score; MHR, monocyte-to-high-density lipoprotein ratio; NLR, neutrophil-to-lymphocyte ratio; SII, systematic immune-inflammation index; SIRI, systemic inflammation response index; T, tertile.

Statistical significance was defined under two-tailed conditions.