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. 2022 Sep 9;10:1000556. doi: 10.3389/fped.2022.1000556

TABLE 4.

Univariable and multivariable analysis for global myocardial work parameters.

Univariable analysis
Multivariable analysis
Standardized coefficients P-value Standardized coefficients P-value
Global work index (mmHg%)
SBP 0.508 <0.001 0.843 <0.001
DBP 0.157 0.052
LVM/height2.7 0.190 0.018
E/e′ 0.277 0.001 0.148 <0.001
LVEF 0.315 <0.001
LV GLS –0.474 <0.001 –0.777 <0.001
Global constructive work (mmHg%)
SBP 0.539 <0.001 0.878 <0.001
DBP 0.192 0.017
LVM/height2.7 0.138 0.086
E/e′ 0.225 0.005 0.099 0.002
LVEF 0.334 <0.001
LV GLS –0.471 <0.001 –0.796 <0.001
Global wasted work (mmHg%)
Age 0.194 0.016
BSA 0.167 0.037
SBP 0.217 0.007
DBP 0.242 0.002
IVSd 0.173 0.031
E/A –0.227 0.005 –0.165 0.038
LV GLS 0.287 <0.001
PSD 0.300 <0.001 0.250 0.002
Global work efficiency (%)
Age –0.169 0.036
BSA –0.170 0.034
DBP –0.196 0.015
IVSd –0.182 0.023
E/A 0.224 0.005 0.162 0.036
LV GLS –0.404 <0.001 –0.306 <0.001
PSD –0.299 <0.001 –0.208 0.007

SBP, systolic blood pressure; DBP, diastolic blood pressure; LVM, left ventricular mass; BSA, body surface area; IVSd, interventricular septal diameter; LVEF, left ventricular ejection fraction; E, early mitral inflow velocity; A, late mitral inflow velocity; e′, peak early diastolic velocity of the septal mitral annulus (tissue Doppler image); LV GLS, left ventricular global longitudinal strain; PSD, peak strain dispersion.