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. 2022 Jun 22;14(4):947–963. doi: 10.1016/j.jcmgh.2022.05.015

Figure 1.

Figure 1

Endocannabinoid synthesis and degradation pathways. Synthesis and degradation of the 2 major endocannabinoids, anandamide (A) and 2-AG (B). Further details are provided in the text. 2-AG, 2-arachidonoylglycerol; DAGL, diacylglycerol lipase; FAAH, fatty acid amide hydrolase; GDE1, glycerophosphodiesterase E1; MAGL, monoacylglycerol lipase; NAPE-PLD, N-acylphosphatidylethanolamine-hydrolyzing phospholipase D; PI, phosphatidylinositol; PLA, phospholipase A; PLC, phospholipase C; PLD, phospholipase D; PTPN22, protein tyrosine phosphatase non-receptor type 22. Figure created with BioRender.com.