TABLE 1.
Clinical application of R. cordifolia in traditional prescriptions.
| Classic prescriptions | Composition of medicines | Symptoms of treatment | Type and number of participants | References |
|---|---|---|---|---|
| Puji Benshifang | R. cordifolia, Artemisia argyi Levl.et Vant, Prunus mume (Sieb.) Sieb.et Zuce | Treatment of nosebleeds | 50 patients with nosebleeds. (age range, 14–76 years old) | (Li, 2000; Meng, 2010) |
| Qixiongwan | R. cordifolia, Aconitum kusnezoffii Reichb, Moschus, Terminalia chebula Retz, Ruta graveolens L, Mercury (II) Sulfide, O. chiliophyllaRoyle | Treatment of Mycoplasma pneumoniae pneumonia | 21 patients with positive serum mycoplasma antibody test. (age range, 3–39 years old) | Du, (2002) |
| Shengjie zonglu | R. cordifolia, Glycyrrhiza uralensis Fisch | Treatment of vomiting blood, antipyretic and thirst, detoxification | 60 patients (36 female and 24 male) with fever. (age range, 15–60 years old) | (Gupta et al., 2008; Li and Meng, 2018; Wang et al., 2022) |
| Sanhongtang | R. cordifolia, Eriobotrya japonica Thunb, Laccifer lacca Kerr | Treatment of kidney damage, lung heat, cough, blood in sputum, bladder heat, dysuria and frequent urination | Not available | Larga et al. (2021) |
| Sanwei Chafenliaotang | R. cordifolia, Ophiopogon japonicus (Linn. f.) Ker-Gawl, Polygonum divaricatum L | Treatment of fever in the lungs and tingling in the intestines | Not available | Liu et al. (2021) |
| Sibu Yidian | R. cordifolia, Terminalia chebula Retz. Laccifer lacca Kerr. Symplocos caudata Wall | Treatment of kidney and enteric fever | Not available | Niang et al. (2021) |
| Shisanwei Ximingwan | R. cordifolia, Patrinia scabiosaefolia, Erminalia chebula Retz, Laccifer lacca Kerr, Caesalpinia decapetala (Roth) Alston, Mangifera indica L, Syzygium jambos (L.) Alston, Shanfanshi, Cupressus funebris Endl, Amomum cardamon, Herpetospermum pedunculosum (Ser.) C. B, veronica eriogyne H. Wink | Treatment of chronic prostatitis | 93 patients with chronic prostatitis. (age range, 30–60 years old) | (Zhou, 2017; Liu et al., 2020) |
| Tangyao Jingyanfang | R. cordifolia, Asini Corii Colla, Platycladus orientalis (L.) Franco, Platycladus orientalis (L.) Franco | Pentecostal acts for healing women | 181 patients with blood deficiency. (age range, 18–60 years old) | (Li and Meng, 2018; Zhang et al., 2021) |
| Taiping Shenghuifang | R. cordifolia, Punica granatum L | Treatment of prolapse of the anus and menorrhagia | 48 female patients. (age range, 15–50 years old) | (Shen, 2013; Bryant-Smith et al., 2018) |
| Yiashen Shiqiweiwan | R. cordifolia, Terminalia chebula Retz, Moschus, Aconitum kusnezoffii Reichb, Acorus tatarinowii, Aucklandia lappa Decne, Haliotis discus hannai, Mercury (II) Sulfide, Pulvis billis bovis, Ruta graveolens L. Canavalia gladiata (Jacq.) DC, Carthamus tinctorius L, Eriobotrya japonica Thunb, Xiangmo, Amomum kravanh Pierre ex Gagnep, Laccifer lacca Kerr. Dashua Jihua | Treatment of chronic epididymal and spermatic hydrocele | 324 patients with chronic epididymis. (age range, 7–89 years old) | (Wu, 2008a; Wu, 2008b; Wang, 2013) |
| 32 patients with hydrocele of the spermatic cord. (age range, 3–12 years old) |
Not available: The combination of R. cordifolia and other drugs for the treatment of some diseases has been recorded in traditional Chinese prescriptions, but these clinical data have not been reported in any literatures.