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. 2022 Sep 8;14(18):3710. doi: 10.3390/nu14183710

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of B. coagulans SNZ 1969 on plasma gastrointestinal hormones in loperamide-induced constipation rats. NOR: Normal group, LOP: Loperamide treated group; BIS: Loperamide and Bisacodyl 8 mg/kg treated group; SNZ-L: Loperamide and B. coagulans SNZ 1969 at 1 × 10⁸ CFU/day treated group; SNZ-H: Loperamide and B. coagulans SNZ 1969 at 1 × 10¹⁰ CFU/day treated group. Concentrations of (A) Gastrin, (B) Substance P, (C) Cholecystokinin, (D) Somatostatin, and (E) Vasoactive intestinal peptide in plasma were estimated by ELISA. The results are presented as mean ± SE (n = 8). Means with the different letters above a bar are significantly different at p < 0.05 by Duncan’s multiple range test. NS: not significant.

Effects of B. coagulans SNZ 1969 on plasma gastrointestinal hormones in loperamide-induced constipation rats. NOR: Normal group, LOP: Loperamide treated group; BIS: Loperamide and Bisacodyl 8 mg/kg treated group; SNZ-L: Loperamide and B. coagulans SNZ 1969 at 1 × 10⁸ CFU/day treated group; SNZ-H: Loperamide and B. coagulans SNZ 1969 at 1 × 10¹⁰ CFU/day treated group. Concentrations of (A) Gastrin, (B) Substance P, (C) Cholecystokinin, (D) Somatostatin, and (E) Vasoactive intestinal peptide in plasma were estimated by ELISA. The results are presented as mean ± SE (n = 8). Means with the different letters above a bar are significantly different at p < 0.05 by Duncan’s multiple range test. NS: not significant.