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. 2022 Aug 30;9(9):287. doi: 10.3390/jcdd9090287

Table 1.

Changes in cardiovascular outcomes within- and between groups.

IHG-60 (n = 12) IHG-30 (n = 13) CON (n = 14) Between-Groups
Variable Pre Post Delta Score Pre Post Delta Score Pre Post Delta Score p-Value
FMD (%) 5.65
(3.15, 7.35)
9.18
(5.0, 12.99)
4.05
(1.65, 5.45), p = 0.002 **
5.83
(4.46, 7.07)
8.15
(6.52, 9.89)
2.17
(1.69, 2.63),
p = 0.001 **
6.04
(4.66, 6.83)
5.54
(4.2, 6.6)
−0.34
(−0.69, 0.05),
p = 0.03 *
X2 = 27.29, p < 0.001 **
Resting HR (bpm) 71.5
(65.5, 78.0)
67.0
(61.75, 73.75)
−4.0
(−5.0, −4.0), p = 0.002 **
74.0
(67.5, 77.5)
72.0
(65.5, 75.5)
−2.0
(−2.5, −1.0), p = 0.001 **
76.0
(67.75, 78.5)
75.0
(67.25, 80.25)
1.0
(−1.0, 1.0), p = 0.516
X2 = 21.70, p < 0.001 **
Heart rate variability
SDNN
(ms)
54.0
(39.0, 67.25)
60.50
(44.75, 67.0)
5.0
(2.0, 11.5), p = 0.017 **
54.0
(40.5, 77.0)
55.0
(44.0, 78.0)
4.0
(1.5, 6.5), p = 0.002 **
53.0
(48.5, 64.5)
57.0
(52.5, 64.75)
4.5
(2.75, 6.25), p = 0.002 **
X2 = 0.86, p = 0.652
PNN50
(%)
16.0
(13.25, 19.50)
18.0
(14.5, 21.75)
2.0
(1.0, 3.0), p = 0.005 **
18.0
(14.0, 24.0)
18.0
(16.0, 26.5)
2.0
(0, 3.0),
p = 0.019 *
17.5
(14.75, 20.25)
20.5
(16.75, 21.5)
2.0
(1.0, 3.0), p = 0.001 **
X2 = 0.58, p = 0.750
HF
(nu)
705.50
(403.50, 879.50)
674.0
(442.5, 927.5)
72.0
(−60.0, 120.75), p = 0.347
812.0
(355.0, 935.0)
793.0
(407.0, 991.0)
48.0
(−4.5, 76.0), p = 0.036 *
678.0
(566.75, 792.0)
715.5
(648.75, 840.0)
37.5
(3.0, 69.75), p = 0.109
X2 = 1.23, p = 0.541
LF
(nu)
1378.0
(996.0, 2104.0)
1329.5
(893.0, 2002.5)
−89.5
(−104.75, −11.5), p = 0.015 *
1320.0
(983.5, 2022.0)
1312.0
(945.5, 2013.0)
−24.0
(−56.5, −6.5), p = 0.087
1267.0
(1066.75, 1717.75)
1260.5
(1028.75, 1648.75)
−46.0
(−74,25, −15.0), p = 0.002 **
X2 = 3.51, p = 0.173
LF/HF 2.4
(1.38, 4.58)
2.0
(1.43, 2.98)
−0.3
(−0.73, 0.13), p = 0.084
1.6
(1.1, 4.8)
1.7
(1.0, 4.1)
−0.2
(−0.6, −0.02), p = 0.007 **
1.9
(1.45, 4.33)
1.85
(1.5, 3.45)
−0.25
(−0.85, 0.2), p = 0.161
X2 = 0.16, p = 0.922

FMD = flow-mediated dilation; HR = heart rate; IHG-60 = isometric handgrip performed at 60% maximal voluntary contraction; IHG-30 = isometric handgrip performed at 30% maximal voluntary contraction; CON = control. Data presented as median (interquartile range). Significant effects * p < 0.05; ** p < 0.01.