TABLE 5.
List of proteins secreted by type I secretion system and content of cysteine residues
| Secreted protein (gene) | Microorganism | Components of type I secretion system | No. of cysteine residues | Reference |
|---|---|---|---|---|
| Protease AB374 (prtA) | Erwinia chrysanthemi | PrtD, PrtE, PrtF | 0 | 27 |
| Protease B (prtB) | Erwinia chrysanthemi | PrtD, PrtE, PrtF | 0 | 19 |
| Protease CE374 (prtC) | Erwinia chrysanthemi | PrtD, PrtE, PrtF | 0 | 20 |
| Protease CEc16 (prtC) | Erwinia chrysanthemi | PrtD, PrtE, PrtF | 0 | 17 |
| Protease G (prtG) | Erwinia chrysanthemi | PrtD, PrtE, PrtF | 0 | 28 |
| Protease A (prtA) | Erwinia amylovora | PrtD, PrtE, PrtF | 0 | 70 |
| Protease W (prtW) | Erwinia carotovora | Not yet identified | 0 | 46 |
| Adenylate cyclase (cyaA) | Bordetella pertussis | CyaB, CyaD, CyaE | 0 | 29 |
| Alpha-hemolysin (hlyA) | Escherichia coli | HlyB, HlyD, TolC | 0 | 61 |
| Alpha-hemolysin (hlyA) | Escherichia coli | HlyB, HlyD, TolC | 0 | 60 |
| Leukotoxin (pllktA) | Pasteurella haemolytica | PllktB, PllktD | 1 | 14 |
| Metalloprotease (prt) | Serratia sp. strain E-15 | PrtD, PrtE | 0 | 50 |
| Hb binding protein (hasA) | Serratia marcescens | PrtDSM, PrtESMa | 0 | 44 |
| Protease SM (prtSM) | Serratia marcescens | PrtDSM, PrtESM, PrtFSM | 0 | 12 |
| S-layer protein (rsaA) | Caulobacter crescentus | RsaD, RsaE | 0 | 4 |
| Lipase A (lipA) | Serratia marcescens Sr41 | LipB, LipC, LipD | 0 | 2 |
| Lipase A (lipA) | Pseudomonas strain LS107d2 | Not reported yet | 0 | 37 |
| Thermostable lipase (tliA) | Pseudomonas fluorescens | tLiD, tLiE, tLiF | 0 | 1 |
| Protease A (prtA) | Pseudomonas fluorescens | PrtD, PrtE, PrtF | 0 | 1 |
| Alkaline protease (aprA) | Pseudomonas aeruginosa | AprD, AprE, AprF | 0 | 23 |
| Metalloprotease (zapA) | Proteus mirabilis | PrtD, PrtE, PrtF | 0 | 65 |
| Nodulating protein (nodO) | Rhizobium leguminosarum | Not yet reported | 1 | 24 |
a
PrtDSM and PrtESM components of the HasA secretion machinery have been renamed as HasB and HasD, respectively, and HasF, a TolC analog, has been cloned (8).