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. 2022 Sep 19;23(18):10979. doi: 10.3390/ijms231810979

Table 2.

Tyrosinase inhibition activity of oxadiazole-based furan molecules 5a–j.

Compound Tyrosinase Inhibition IC50 (µM)
5a 11 ± 0.25
5b 12.4 ± 0.0
5c 12.7 ± 0.0
5d 15.5 ± 0.0
5e 25 ± 0.75
5f 27 ± 1.00
5g 30 ± 1.50
5h 36 ± 0.25
5i 48 ± 0.96
5j 49.5 ± 0.92
Ascorbic acid
Standard [43,44,45,47,48,49]
11.5 ± 1.00