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Chronic cold exposure promotes the apoptotic pathway and reduces the expression of brain-derived neural factor in lungs. (A) Bax mRNA expression. (B) B-cell lymphoma 2 (Bcl2) mRNA expression. (C) Caspase3 mRNA expression. (D) STAT3 mRNA expression. (E) BDNF mRNA expression. (F) Neurotrophic receptor tyrosine kinase 2 (Trkb) mRNA expression. (G) Bax protein expression. Data are expressed as the mean ± SEM, n = 6, * p < 0.05, ** p < 0.01.
