TABLE 2.
Virulence of V. vulnificus strains in mice and their resistance to human serum
| Straina | LD50 (CFU/mouse) for:
|
Bacterial resistance to human serum (%)b
|
||
|---|---|---|---|---|
| Normal mouse | Iron-overloaded mouse | Untreated | Heat inactivated | |
| YJ016 | 1.0 × 106 | <1.0 × 101 | 25.6 ± 11.7 | 35.9 ± 4.4 |
| CP156 | 2.0 × 106 | <1.0 × 101 | 46.3 ± 11.6 | 38.9 ± 9.6 |
| YJ024 | 3.2 × 107 | 9.5 × 105 | 0 ± 0 | 53.8 ± 3.8 |
a
YJ016, wild-type strain; CP156, RD mutant; YJ024, translucent mutant of YJ016.
b
Bacterial resistance to human serum, either untreated or heated at 56°C for 30 min to inactivate the complement, is expressed as 100% × (the number of viable bacteria after treatment/the number of viable bacteria before treatment). Values represent means ± standard deviations.