Table 5.
S.No. | Unit Operation | Process Parameter |
---|---|---|
1 | Polymer dissolution | Process Temperature |
Stirring speed | ||
Stirring Time | ||
2 | Preparation of micelles | Process Temperature |
Homogenization Speed | ||
Homogenization Time | ||
3 | Extrusion process | Process Temperature |
Number of Cycles | ||
Membrane Pore Size | ||
Pump Speed | ||
4 | Dia-filtration (Removal of ions) | Conductivity of Filtrate |
Process Temperature | ||
Pump Speed | ||
5 | Drug Loading | Process Temperature |
Stirring Speed | ||
Incubation Time | ||
6 | Filtration | Filter Flushes |
Filter Integrity | ||
Filtration Time | ||
Filtration Pressure |