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Tests and sample sizes.
| Test | 4-Month | 8-Month | ||
|---|---|---|---|---|
| 3xTg-AD | Control | 3xTg-AD | Control | |
| Morris Water Maze (MWM) | 8 | 8 | 6 | 8 |
| Social discrimination (SD) | 8 | 8 | 6 | 8 |
| Open field (OF) | 8 | 8 | 6 | 8 |
| Elevated plus maze (EPM) | 10 | 11 | 8 | 8 |
| Light-dark box (LD) | 11 | 10 | 7 | 12 |
| Novelty suppressed feeding (NSF) | 8 | 10 | 10 | 14 |
| Social interaction (SI) | 11 | 10 | 7 | 12 |
| Forced swim test (FST) | 8 | 10 | 13 | 14 |
| Tail suspension test (TST) | 9 | 10 | 14 | 14 |
| Splash | 9 | 10 | 12 | 13 |
| Sucrose preference test (SPT) | 9 | 10 | 14 | 14 |
| Learned helplessness (LH) | 9 | 10 | 14 | 11 |
