Table 1.
Summary of factors that affect expression of miRNAs in human trophoblasts.
| Factors | Affected miRNAs in Human Trophoblasts | ||
|---|---|---|---|
| Hypoxia | Up-regulated | miR-210 [81], miR-141 [82], miR-218 [83] | |
| Environment Factors | Phthalate | Up-regulated | miR-17-5p [88], miR-155-5p [88], miR-126-3p [88], miR-16 [89] |
| Bisphenol A | Up-regulated | miR-146a [90] | |
| Phenol | Up-regulated | miR-142-3p [91], miR15a-5p [91], miR-185 [91] | |
| Epigenetic Regulation | Methylation | Up-regulated | C19MC [95] |
| Single-Nucleotide Polymorphism (SNP) | - | 27 miRNAs [96], miR-126 [97], miR-143 [97], miR-143 [97] | |