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. 2022 Aug 26;15(9):1056. doi: 10.3390/ph15091056

Table 2.

Differential metabolites related to atherosclerosis in GPE treated HFCD diet group compared with HFCD diet.

Metabolite Fold Change
D-Cellobiose 22.449
Tyramine 13.37
Melibiose 13.235
Dihydro-cholesterol 12.633
5-Methoxytryptamine 10.771
4-O-Hexopyranosylhex-2-ulofuranose 9.1412
D-Galacturonic cid 8.8722
Hydroxyproline 7.9615
3-Methyl-2-oxobutanoic acid 5.8605
Hexose 5.4677
3-Methyl-2-oxovalerate 5.4058
Oxalacetic acid 5.0682
L-Phenylalanine 3.7558
3-Methyl-2-oxopentanoate 3.7309
4-Methyl-2-oxopentanoate 3.6265
Malbit 3.5755
Deoxyadenosine 3.5743
Galactosyl-glycerol 3.5642
L-Gulcono-1,4-lactone 3.2961
N-Methyl-DL-alanine 3.0154
D-Lyxose 2.9811
L-Iditol 2.9403
2-O-Methyl-D-mannopyranosa 2.5005
Pentose 2.4453
Deoxyinosine 2.323
Pantothenic acid 2.1301
Pseudo-uridine 2.0331
Thymine 1.9163
D-Tagatose 1.8483
D-Glucose 1.7846
2,5,7,8-Tetramethyl-2-(5,9,13-trimethyltetradecyl)-3,4-dihydro-2h-chromen-6-ol 1.7703
Linoleate 1.7462
Aldohexose 1.5223
Aminomalonate 1.2711
Di-isopropanolamine 1.268
Glycerol 0.6751
Hexa-decanoic acid 0.6641
Propane-1,3-diol 0.66263
Lactic acid 0.66201
gamma-Aminobutyric acid 0.59821
L-Alanyl-L-alanine 0.53075
Glycolic acid 0.52183
Octadecanoic acid 0.51757
Malic acid 0.46053
Chimyl alcohol 0.41685
4-Hydroxylphenyllactic acid 0.38248
Cholestanol 0.3759
Batyl alcohol 0.37026
2,3-Bisphospho-glyceric acid 0.29243
Creatine 0.28688
2,3-Diaminopropionic acid 0.26765
3-Epicholic acid 0.19065
Icosanoic acid 0.18807
11beta-Hydroxyandrostenedione 0.15355
4-Hydroxyphenylacetic acid 0.14495
1-Eicosanol 0.13899
Butenedioic acid 0.11864
2-Deoxy-D-galactose 0.11572
L-Aspartate 0.097594
Octadecanol 0.070298
3,4-Dihydroxyphenylacetic acid 0.028664
Cholan-24-oic acid, 3,7,12-trihydroxy-, (3alpha,5beta,7alpha,12alpha)- 0.0058382
Cholic acid 0.0040922