Figure 5.

ROC analysis—the combination of microRNA biomarkers (miR-20a-5p, miR-20b-5p and miR-195-5p). A total of 30.0% pregnancies destinated to develop GDM requiring a combination of diet and administration of appropriate therapy had aberrant microRNA expression profile in the whole peripheral venous blood during the first trimester of gestation at a 10.0% FPR. This represents 6 out of 20 pregnancies correctly predicted to develop GDM and 8 out of 80 normal pregnancies predicted false positively to develop GDM.