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. 2022 Sep 16;14(9):2053. doi: 10.3390/v14092053

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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First norovirus episodes induce durable blockade antibody responses in young children. Additional serum samples from the infected children with serological data presented in Figure 3 and Figure 4 were collected over a 2-to-3-year period and analyzed for blockade antibody titer to the infecting genotype: GII.4 Sydney (•), GII.12 (•) and GI.3/GI.5 (•). Marker: one child. X axis: time period in months relative to first AGE episode. Line and error bars: geometric mean and 95% confidence intervals. Dashed line: assay limit of detection.