Table 1.
Subject ID | Gender | Poverty Index * | Severity Score ** | Pre-Existing Blockade Antibodies † | Norovirus Genotype in Stools | GII Blockade Response ⋆ | GI Blockade Response ⋆ |
---|---|---|---|---|---|---|---|
1 | M | 1 | 4 | GII.2, GI.1, GI.5 | GII.4 Sydney [P31] | GII.4 Sydney | - |
2 | F | 2 | 4 | - | GII.4 Sydney [P16] | GII.4 Sydney | - |
3 | M | 1 | 7 | - | GII.4 Sydney [P16] | GII.4 Sydney | - |
4 | F | 2 | 7 | - | GII.4 Sydney [P16] | GII.4 Sydney | - |
5 | M | 2 | 9 | GII.12 | GII.4 Sydney [P16] | GII.4 Sydney | - |
6 | M | 2 | 8 | GII.12, GI.1, GI.4, GI.5, GII.4 Den Haag, GI.7, GII.4 Sydney | GII.4 Sydney [P16] | GII.4 Sydney | - |
7 | F | 2 | 9 | GI.4, GII.14 | GII.4 Sydney [P16] | GII.4 Sydney | - |
8 | F | 1 | 8 | GII.2 | GII.4 Sydney [P16] | GII.4 Sydney | - |
9 | M | 2 | 5 | GII.2 | GII.12 [P16] | GII.12 | - |
10 | M | 1 | 6 | GII.2, GI.3, GII.14, GI.1, GI.5, GII.4 Den Haag, GI.7, GII.4 Sydney, GII.3, GII.17, GI.4, GII.12 | GII.12 [P16] | GII.12 | - |
11 | M | 1 | 7 | GII.4 Den Haag, GII.4 Sydney, GII.2, GII.12, GI.5, GII.14, GI.1 | GII.12 [P16] | GII.12 | - |
12 | M | 1 | 4 | - | GI.3 [P3] | - | GI.3 |
13 | M | 1 | 8 | GII.17, GII.4 Sydney, GII.4 Den Haag | GI.5 [P4] | - | GI.3 |
14 | F | 2 | 3 | - | GI.5 [P4] | - | GI.5 |
15 | F | 1 | 3 | - | GII.4 Sydney [P31] | GII.4 Sydney, GII.12, GII.2, GII.3, GII.17 | - |
16 | M | 1 | 15 | - | GII.4 Sydney [P31] | GII.4 Sydney, GII.12, GII.2 | - |
17 | M | 1 | 8 | - | GII.4 Sydney [P16] | GII.4 Sydney, GII.12, GII.2, GII.3 | - |
18 | M | 0 | 8 | GII.2, GI.5, GI.1, GII.3, GI.7, GII.4 Den Haag, GII.4 Sydney | GII.4 Sydney [P31] | GII.4 Sydney, GII.12 | - |
19 | M | 2 | 4 | - | GII.12 [P16] § | GII.4 Sydney, GII.12 | - |
20 | M | 2 | 3 | GI.1, GI.5, GI.7 | GII.12 [P16] | GII.4 Sydney, GII.12 | - |
21 | M | 1 | 5 | - | GII.4 Sydney [P16] | GII.4 Sydney, GII.14, GII.2 | - |
22 | F | 0 | 5 | GII.2, GII.4 Den Haag | GI.3 [P3] | - | GI.3, GI.4, GI.5, GI.6 |
23 | M | 1 | 4 | GI.7, GI.1, GI.3, GI.5, GII.4 Den Haag | GI.5 [P4] | GII.12 | GI.3, GI.5 |
24 | M | 2 | 3 | GII.12 | GII.4 Sydney [P16] | GII.4 Sydney | GI.3, GI.4, GI.5 |
25 | F | 2 | 7 | GII.12 | GII.4 Sydney [P16] | GII.4 Sydney, GII.3 | GI.1 |
26 | M | 2 | 4 | GII.2, GII.3 | GI.3 [P3] | GII.4 Sydney, GII.12 | GI.3, GI.5 |
* Poverty index: 0, No poverty; 1, Poverty; 2, Extreme poverty. ** Episode severity score was defined using a scale of 0–15, in which points were assigned based on symptom severity (diarrhea, vomiting, maximum of stools per day, presence of fever and if they received intravenous fluid for dehydration) [37,45]. ⋆ Response was defined as >4-fold increase over baseline. † Ordered from highest to lowest titer. § A second symptomatic episode due to GII.4 Sydney (11 months of age) was collected within pre-and post-serum testing.