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Representation of 3D tumor spheroids: in vitro cytotoxicity of albumin-stabilized mitotane (BSA-MT), liposomal mitotane (DOPC-MT), and free mitotane (MT). Cell viability of NCI-H295R 3D multicellular tumor spheroids was analyzed using the CellTiter-Glo® 3D cell viability assay (A) 24 h and (B) 72 h after sample treatment. Data are expressed as mean ± SD, n = 3.
