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. 2021 Nov 22;40(5):625–634. doi: 10.1159/000521062

Table 3.

Genotype counts and frequency of rs38409 G allele for cirrhosis-related complications

Etiology Complication present, n (%) Complication absent, n (%) OR 95% CI p value
Total 199 (49.8) 201 (50.3)
CC = 37 (18.6) CC = 201 (25.4) 1 Reference
CG = 90 (45.2) CG = 103 (51.2) 1.204 0.724–2.004 0.474
GG = 72 (36.2) GG = 47 (23.4) 2.112 1.205–3.699 0.009
C allele = 164 (41.2) C allele = 205 (51.0) 1 Reference
G allele = 234 (58.8) G allele = 197 (49.0) 1.401 0.916–2.144 0.120

Virus 75 (47.7) 82 (52.3)
CC = 22 (29.3) CC = 25 (30.5) 1 Reference
CG = 40 (53.3) CG = 37 (45.1) 1.229 0.594–2.541 0.579
GG = 13 (17.3) GG = 20 (24.4) 0.739 0.299–1.823 0.511
C allele = 84 (56) C allele = 87 (53) 1 Reference
G allele = 66 (44) G allele = 77 (47) 0.904 0.458–1.786 0.771

Alcohol 57 (54.8) 47 (45.2)
CC = 7 (12.3) CC = 11 (23.4) 1 Reference
CG = 30 (52.6) CG = 23 (48.9) 2.050 0.688–6.110 0.198
GG = 20 (35.1) GG = 13 (27.7) 2.418 0.745–7.845 0.142
C allele = 44 (38.6) C allele = 45 (47.9) 1 Reference
G allele = 70 (61.4) G allele = 49 (52.1) 1.371 0.592–3.176 0.460

NAFLD 51 (48.1) 55 (51.9)
CC = 7 (13.7) CC = 9 (16.4) 1 Reference
CG = 12 (23.5) CG = 33 (60.0) 0.468 0.142–1.534 0.210
GG = 32 (62.7) GG = 13 (23.6) 3.165 1.073–10.294 0.046
C allele = 26 (25.5) C allele = 51 (46.4) 1 Reference
G allele = 76 (74.5) G allele = 59 (53.6) 2.260 0.922–5.544 0.075

AID 16 (48.5) 17 (51.5)
CC = 1 (6.3) CC = 6 (35.3) 1 Reference
CG = 8 (50) CG = 10 (58.8) 4.800 0.475–48.46 0.184
GG = 7 (43.8) GG = 1 (5.9) 42.00 2.136–825.7 0.014
C allele = 10 (31.3) C allele = 22 (64.7) 1 Reference
G allele = 22 (68.8) G allele = 12 (35.3) 3.088 0.673–14.166 0.144