Table 1.

The predicted PDE5 IC₅₀ values of the test set (series A–H) in nM.

Compound	Predicted IC50 (nM)	Compound	Predicted IC50 (nM)
5a	202.71	8i	71.38
5b	262.99	8j	137.24
5c	147.43	9a	39.33
6a	51.38	9b	99.61
6b	70.36	9c	58.31
6c	7.83	9d	−4.21
7a	90.20	9e	66.24
7b	120.98	10a	125.77
7c	147.98	10b	186.05
8a	27.49	10c	70.48
8b	26.75	11a	49.54
8c	38.97	11b	68.52
8d	81.56	11c	6.00
8e	66.27	12a	111.41
8f	66.27	12b	171.69
8g	66.27	12c	130.39
8h	141.84	12d	67.86