Table 2.

Some IC₅₀ values of the most active derivatives against different cancer cell lines.

Compound	Cancer Cell Line	IC50 Value
22f	HeLa	7.76 ± 0.98 μM [64]
28e	SK-OV-3	1.79 ± 0.43 μM [65]
30n	HeLa	6.58 ± 1.11 μM [66]
36w	HeLa	2.21 ± 0.04 μM [69]
36w	BEL-7402	14.46 ± 0.22 μM [69]
39j	MGC-803	3.82 ± 0.18 μM [70]
41c	HepG2	5.90 ± 0.41 μM [71]
41k	HepG2	6.25 ± 0.37μM [71]
43b	MCF-7	7.00 ± 0.96 μM [72]
47n	BEL-7402	11.23 ± 0.21 μM [73]
47j	CNE-2	8.36 ± 0.14 μM [73]
63r	HepG2	24.41 ± 0.26 μM [81]
63s	HepG2	22.92 ± 0.24 μM [81]
67g	SMMC-7721	1.39 ± 0.13 μM [82]
67g	HepG2	0.51 ± 0.09 μM [82]
67g	Hep3B	0.73 ± 0.08 μM [82]
69p	MDA-MB-231	0.7 ± 0.1 μM [84]
74b	SMMC-7721	0.36 ± 0.13 μM [86]
74e	HepG2	0.12 ± 0.03 μM [86]
77b	SMMC-7721	0.72 ± 0.09 μM [87]
79h	MCF-7	0.87 ± 0.18 μM [88]
80j	SMMC-7721	0.08 ± 0.01 μM [89]
84a	HCT-116	1.18 ± 0.52 μM [90]