Table 3.
Outcomes | Anticipated absolute effects * (95% CI) | Relative effect (95% CI) | No. of participants (trials) | Certainty of the evidence (GRADE) | |
---|---|---|---|---|---|
Risk with control | Risk with acupuncture | ||||
Clinical pregnancy rate | 324 per 1,000 | 499 per 1,000 (415–599) |
RR 1.54 (1.28–1.85) |
1130 (14 RCTs) |
⊕⊕○○ Lowa, b |
Biochemical pregnancy rate | 384 per 1,000 | 580 per 1,000 (465–726) |
RR 1.51 (1.21–1.89) |
354 (5 RCTs) |
⊕⊕○○ Lowa, c |
Live birth rate | 324 per 1,000 | 480 per 1,000 (292–788) |
RR 1.48 (0.90–2.43) |
431 (4 RCTs) |
⊕⊕○○ Lowa, d |
Endometrial thickness | – | MD 0.97 higher (0.43 higher−1.51 higher) |
– | 836 (12 RCTs) |
⊕⊕⊕○ Moderatea |
Endometrial pattern | 592 per 1,000 | 835 per 1,000 (669–1,000) |
RR 1.41 (1.13–1.75) |
413 (7 RCTs) |
⊕⊕⊕○ Moderatea |
The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
Part of the trials did not provide details on allocation concealment or blinding;
Only a few negative results were reported;
The sample size was small;
Only a few trials reported the outcome and the 95%CI was wide.