Table 5. Comparison of the Exposure of High (P95) Milk Consumers to the Lowest Single Oral Effective Dose for QAa.
population group | high consumer (P95) |
|
---|---|---|
QA content in cow’s milk (μg/kg) | ||
BSL-1 | BSL-2 | |
max | max | |
19607.3 | 90186.5 | |
comparison of exposure to toxicological reference point expressed as MoE | ||
infants | 0.04 | 0.01 |
toddlers | 0.11 | 0.02 |
other children | 0.18 | 0.04 |
adolescents | 0.41 | 0.09 |
adults | 0.72 | 0.16 |
elderly | 0.93 | 0.20 |
very elderly | 0.96 | 0.21 |
pregnant woman | 0.77 | 0.17 |
lactating woman | 0.92 | 0.20 |
The EFSA Rapid Assessment of Contaminant Exposure (RACE) tool was used for calculation of different exposure scenarios. Maximum QA in the milk during BSL-1 and BSL-2 of the feeding experiment and a lowest single oral effective dose of 0.16 mg sparteine/kg bw/d were taken as a basis. Bold numbers: exceedance of MoE 1.