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. 2022 Sep 6;70(37):11749–11758. doi: 10.1021/acs.jafc.2c02517

Table 5. Comparison of the Exposure of High (P95) Milk Consumers to the Lowest Single Oral Effective Dose for QAa.

population group high consumer (P95)
  QA content in cow’s milk (μg/kg)
  BSL-1 BSL-2
  max max
  19607.3 90186.5
  comparison of exposure to toxicological reference point expressed as MoE
infants 0.04 0.01
toddlers 0.11 0.02
other children 0.18 0.04
adolescents 0.41 0.09
adults 0.72 0.16
elderly 0.93 0.20
very elderly 0.96 0.21
pregnant woman 0.77 0.17
lactating woman 0.92 0.20
a

The EFSA Rapid Assessment of Contaminant Exposure (RACE) tool was used for calculation of different exposure scenarios. Maximum QA in the milk during BSL-1 and BSL-2 of the feeding experiment and a lowest single oral effective dose of 0.16 mg sparteine/kg bw/d were taken as a basis. Bold numbers: exceedance of MoE 1.