Table 1.
Fluconazole (FLZ), ketoconazole (KTC), itraconazole (ITZ), posaconazole (POS), and amphotericin B (AMB) minimum inhibitory concentration (MIC, mg/L) data, standard deviation (SD), MIC range, MIC50, and MIC90 of Malassezia spp. according to the clinical origin.
| Malassezia Species Origin | Fluconazole | Ketoconazole | Itraconazole | Posaconazole | Amphotericin B | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Range | Mean MIC (SD) |
MIC50 | MIC90 | Range | Mean MIC (SD) |
MIC50 | MIC90 | Range | Mean MIC (SD) |
MIC50 | MIC90 | Range | Mean MIC (SD) |
MIC50 | MIC90 | Range | Mean MIC (SD) |
MIC50 | MIC90 | |
| Group 1 (40 isolates) |
32->64 | 40.1 (16.2) |
32 | 64 | 0.125–8 | 1.72 (2.4) |
0.5 | 4 | 0.06–8 | 0.95 * (2.16) |
0.125 | 1 | 0.06–2 | 0.22 * (0.34) | 0.125 | 0.25 | 0.25–8 | 1.79 * (2.08) | 1 | 4 |
| Group 2 (18 isolates) |
4->64 | 35.6 (21.2) |
32 | 64 | 0.06–4 | 0.91 (0.89) |
0.5 | 1 | 0.06–2 | 0.61 * (0.37) |
0.5 | 1 | 0.125–1 | 0.35 * (0.26) | 0.25 | 0.5 | 0.5–4 | 2.42 * (1.39) | 2 | 4 |
| Total | 4->64 | 38 (17.7) |
32 | 64 | 0.06–8 | 1.60 (2.3) |
0.5 | 4 | 0.06–8 | 0.90 (1.8) |
0.25 | 2 | 0.06–2 | 0.26 (0.3) |
0.125 | 0.5 | 0.25–8 | 2.02 (1.9) |
1 | 4 |
* The difference is statistically significant with p value < 0.05.