Table 1.
Sponge species, compound/extract, cell lines tested, metabolomics techniques and corresponding reference are reported.
| Sponge | Compound/Extract | Cell Lines | Metabolomics | Reference |
|---|---|---|---|---|
| S. carteri | Stylissamide A and Stylissoside A | MCF7 and HepG2 | LC-MS | [93] |
| C. siphonella | 5-bromotrisindoline and 6-bromotrisindoline | HT29, OVCAR3 and MM.1S | LC-MS | [94] |
| H. rosea | 3-alkyl pyridine alkaloids | SKBR3 | MS | [95] |
| Coscinoderma sp. | Crude extract | HepG2, MCF7 and Caco2 | LC-MS | [97] |
| G. macandrewii | Geodiataurine | A2058 | UHPLC and MS | [98] |
| L. biformis | (−)-discorhabdin L, (−)-1-acetyl-discorhabdin L and (+)-1-octacosatrienoyl-discorhabdin L | HCT116 | 1H-NMR and MS | [99] |
| T. swinhoei | Theopalauamide, 5-cis-Apoa-theopalauamide and Theonellamide K | HCT116 | 1D and 2D NMR; MS | [100] |
| P. ficiformis | Petrocidin A and 2,3-Dihydroxybenzamide | HL60 and HT29 | LC-MS | [105] |
| Callyspongia sp. | Nocardiotide A | CT26, HeLa and MM.1S | MS | [106] |
| Amphimedon sp. | Crude extract | HepG2, MCF7 and Caco2 | MS | [107] |
| Callyspongia sp. and S. vagabunda | N-(2-hydroxyphenyl)-acetamide | HCT116, HepG2 and MCF7 | LC–MS | [108] |