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. 2022 Aug 31;13(3):137. doi: 10.3390/jfb13030137

Figure 9.

Figure 9

In vivo two-plex NIR-IIb molecular imaging of immune responses using ErNPs-aPDL1 and PbS-aCD8 at the same ~1600 nm emission range. Two-plex molecular imaging (upper right) of a CT-26 tumor mouse at 24 h post intravenous injection of mixed ErNPs-aPDL1 (green color, upper left) and PbS-aCD8 (red color, lower left). Scale bar: 5 mm. The zoomed-in high-magnification two-plex image (lower right) outlined the CT-26 tumor with micrometer image resolution (scale bar: 500 μm). This image has been adapted with permission from Zhong et al. [55] © 2019, Nature Publishing Group.