Table 1.
Laboratory Parameter | February 2010 (Time of Diagnosis) |
November 2012 (CYC 1 Initiation) | November 2014 (First RTX 2
Application) |
August 2018 (First Relapse after RTX) |
December 2021 (Last Visit) |
---|---|---|---|---|---|
Hemoglobin (g/L) | 124 | 117 | 127 | 126 | 132 |
Leukocytes (×106/L) | 9.2 | 5.8 | 7.7 | 5.7 | 9.2 |
Serum creatinine (μmol/L) | 56 | 78 | 308 | 99 | 111 |
eGFR CKD-EPI 3 (ml/min/1.73 m2) | 97 | 70 | 13 | 50 | 43 |
Serum albumin (g/L) | 23 | 24 | 19 | 30 | 42 |
Urea (mmol/L) | 5.2 | 6.4 | 35.2 | 10.4 | n/a |
Total cholesterol (mmol/L) | 10 | 9.8 | 10.9 | 9.7 | 5.75 |
LDL (mmol/L) | 5.77 | 6.4 | n/a | 6.89 | 3.26 |
Triglycerides (mmol/L) | 1.62 | 2.4 | 4.47 | 1.79 | 0.99 |
IgG (g/L) | n/a | 2.58 | n/a | n/a | n/a |
C3 (g/L, ref. 0.9–1.8) | n/a | 1.35 | n/a | n/a | n/a |
C4 (g/L, ref. 0.1–0.4) | n/a | 0.39 | n/a | n/a | n/a |
Complete immunology | Negative | Negative | Negative | Negative | n/a |
Viral hepatitis and HIV 4
serology |
Negative | Negative | Negative | Negative | n/a |
24 h proteinuria (g/day) | 5.08 | 7.54 | 16.7 | 4.2 | 0.16 |
Urine sediment, erythrocytes (per HPF 5) |
8 | 8–10 | 14 | 6 | 0 |
1 cyclophosphamide; 2 rituximab; 3 Chronic Kidney Disease Epidemiology Collaboration; 4 human immunodeficiency virus; 5 high-powered field.