Table 2.
Logistic regression analysis for actionable ADA-HbA1c (defined as prediabetes or diabetes) after adjusting for covariates
Risk factors | Estimated coefficients | P-value | OR | OR (95% CI) | |
---|---|---|---|---|---|
Lower | Upper | ||||
Age (years) | 0.11 | 0.015 | 1.11 | 1.02 | 1.21 |
Ethncity | 1.95 | < 0.001 | 7.05 | 2.94 | 16.92 |
Glucose-lowering drugs (yes) | 1.06 | 0.008 | 2.87 | 1.31 | 6.30 |
FPG at OGTT in pregnancy (mmol/l) | 0.67 | 0.011 | 1.96 | 1.16 | 3.29 |
2-h OGTT glucose in pregnancy (mmol/l) | 0.12 | 0.246 | 1.13 | 0.92 | 1.37 |
Pre-pregnancy BMI (kg) | 0.04 | 0.255 | 1.04 | 0.97 | 1.12 |
GWG (kg) | − 0.03 | 0.366 | 0.98 | 0.92 | 1.03 |
> 3 children (yes) | 0.07 | 0.879 | 1.07 | 0.45 | 2.54 |
Low education (yes) | 0.25 | 0.476 | 1.28 | 0.65 | 2.55 |
1.degree relatives w/diabetes (yes) | 0.66 | 0.070 | 1.93 | 0.95 | 3.91 |
GDM before index pregn (yes) | 1.18 | 0.031 | 3.24 | 1.11 | 9.45 |
Glucose-lowering drugs * GDM before index pregn | − 1.96 | 0.009 | 0.14 | 0.03 | 0.61 |
The model includes the covariates (odds ratio (OR) with 95% CI): age, ethnicity, glucose-lowering drugs, fasting plasma glucose (FPG) and 2-h oral glucose tolerance test (OGTT) values in pregnancy, pre-pregnancy BMI, gestational weight gain (GWG), parity, education, first-degree relatives with diabetes, gestational diabetes mellitus (GDM) before index pregnancy, and the interaction term: Glucose-lowering drugs * GDM before index pregnancy