Table 2.
Compounds | hMAO-A | hMAO-B | SI a |
---|---|---|---|
IC50 (Mean ± SD, µM) | |||
Robinin | >400 | >400 | - |
Quercetin-3-O-robinobioside | >400 | >400 | - |
Rutin | 387.12 ± 4.63 | >400 | - |
Kaempferol-3-O-robinobioside | >400 | >400 | - |
Nicotiflorine | >400 | >400 | - |
Daidzin | >400 | >400 | - |
Genistin | >400 | >400 | - |
Daidzein | 304.05 ± 4.72 | 356.86 ± 1.05 | 0.85 |
Genistein | 4.77 ± 0.51 | 3.42 ± 0.39 | 1.39 |
Coumestrol | 1.99 ± 0.68 | 77.79 ± 2.10 | 0.02 |
Selegiline hydrochloride b | 12.57 ± 0.51 | 0.38 ± 0.001 | 33.08 |
a The selective index (SI) = hMAO-A IC50/hMAO-B IC50. b Positive control.