Table 2.
Patient | Age | Sex | Primary Disease |
Type of Administered ONJ-Related Drugs |
Duration (Months) | Cumulative Dose | Chemo-Therapy | Other Medications |
Other Diseases |
Smoking Habit | MRONJ Location |
---|---|---|---|---|---|---|---|---|---|---|---|
#1 | 52 | F | MTS/BC | Bevacizumab | 4 | 4800 mg | No | No | No | No | Maxilla (single–right side) |
#2 | 74 | M | MTS/PC | Denosumab | 8 | 60 mg | Yes | Prednisone | Hypertension | No | Mandibula (single–right side) |
#3 | 73 | M | MM | Zoledronate | 7 | 5 mg | No | Prednisone | Hypertension and ischemic cardiomyopathy | Yes | Mandibula (single–right side) |
#4 | 49 | M | MTS/PC | Denosumab | 36 | 360 mg | Yes | No | No | Yes | Maxilla and mandibula (multiple–right maxilla and left mandibula) |
#5 | 48 | M | MTS/LC | Denosumab | 12 | 120 mg | No | Nintedanib | No | Yes | Maxilla and mandibula (multiple–right maxilla and left mandibula) |
#6 | 46 | F | MTS/BC | Ibandronate Denosumab Everolimus |
1 38 39 |
3 mg 360 mg 11,700 mg |
Yes | No | No | No | Mandibula (single–left side) |
#7 | 83 | M | MTS/PC | Zoledronate Denosumab |
168 24 |
70 mg 180 mg |
Yes | No | Atherosclerosis | No | Maxilla and mandibula (multiple–left maxilla and mandibula) |
Legend: MM = multiple myeloma; MTS/BC = metastasis/breast cancer; MTS/PC = metastasis/prostate cancer; MTS/LC = metastasis from lung cancer;