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. 2022 Sep 9;11(18):5307. doi: 10.3390/jcm11185307

Table 2.

Descriptive data of enrolled patients.

Patient Age Sex Primary
Disease
Type of
Administered
ONJ-Related Drugs
Duration (Months) Cumulative Dose Chemo-Therapy Other
Medications
Other
Diseases
Smoking Habit MRONJ Location
#1 52 F MTS/BC Bevacizumab 4 4800 mg No No No No Maxilla (single–right side)
#2 74 M MTS/PC Denosumab 8 60 mg Yes Prednisone Hypertension No Mandibula (single–right side)
#3 73 M MM Zoledronate 7 5 mg No Prednisone Hypertension and ischemic cardiomyopathy Yes Mandibula (single–right side)
#4 49 M MTS/PC Denosumab 36 360 mg Yes No No Yes Maxilla and mandibula (multiple–right maxilla and left mandibula)
#5 48 M MTS/LC Denosumab 12 120 mg No Nintedanib No Yes Maxilla and mandibula (multiple–right maxilla and left mandibula)
#6 46 F MTS/BC Ibandronate
Denosumab
Everolimus
1
38
39
3 mg
360 mg
11,700 mg
Yes No No No Mandibula (single–left side)
#7 83 M MTS/PC Zoledronate
Denosumab
168
24
70 mg
180 mg
Yes No Atherosclerosis No Maxilla and mandibula (multiple–left maxilla and mandibula)

Legend: MM = multiple myeloma; MTS/BC = metastasis/breast cancer; MTS/PC = metastasis/prostate cancer; MTS/LC = metastasis from lung cancer;