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. 2022 Sep 17;14(9):2067. doi: 10.3390/v14092067

Figure 3.

Figure 3

Effects of SARS-CoV-2 infection on serum variables in lean hamsters vs. obese NASH hamsters. Blood from the mock-infected and SARS-CoV-2-infected hamsters was collected at different timepoints post-infection. Serum levels of (A) ALT, (B) free fatty acids, (C) triglycerides, (D) HDL cholesterol, (E) LDL cholesterol, and (F) MCP-1 on dpi 4, 7, and 25 are shown. The data are expressed as the mean ± SD (n = 6–8 animals/group). Significant differences between lean hamsters and obese NASH hamsters were determined using the Mann–Whitney U test (* p < 0.05; ** p < 0.01, *** p < 0.001, **** p < 0.0001). The effect of SARS-CoV-2 infection is also depicted. The values were compared with those of mock-infected animals using a Kruskal–Wallis test and Dunn’s post-test (# p < 0.05, ## p < 0.01, and ### p < 0.001).