Table 2.

Comparison of the frequency of genotypes and alleles of individual polymorphisms of MMP-2 and MMP-9 polymorphisms for control groups and patients with type 2 diabetes.

Gelatinase	SNP	Control, n (%)	Patients, n (%)	χ2	p-Value	OR (95%CI)
MMP-2
S. Sarray et al. (2021) [29]	−1306 C/T (rs243865)	Σn = 310	Σn = 791
	genotype
	CC	(64.1)	(73)		0.006	1.00
	CT	(27.3)	(23.3)			0.75 (0.54–1.03)
	TT	(8.6)	(3.7)			0.38 (0.21–0.7)
	CT + TT	(35.9)	(27)			0.66 (0.49–0.89)
	CC + CT	(91.5)	(96.3)		0.003	1.00
	allele frequency
	C	(77.75) *	(84.65) *
	T	(22.25) *	(15.35) *
S. Sarray et al. (2021) [29]	−1575 G/A (rs243866)	Σn = 310	Σn = 791
	genotype
	GG	(66.1)	(74.1)		0.012	1.00
	GA	(30.4)	(23.7)			0.70 (0.51–0.95)
	AA	(3.5)	(2.2)			0.56 (0.25–1.25)
	GA + AA	(33.9)	(25.9)			0.68 (0.51–0.92)
	GG + GA	(96.5)	(97.8)		0.25	1.00
	allele frequency
	G	(81.3) *	(85.95) *
	A	(18.7) *	(14.05) *
MMP-9
K. Singh et al. (2013) [39]	−1562 C/T (rs3918242)	Σn = 267	Σn = 353
	genotype
	CC	196 (73.40)	204 (57.8)			Ref.
	CT	69 (25.84)	137 (57.8)	13.28 *	0.00027 *	1.91 (1.34–2.71) *
	TT	2 (0.75)	12 (3.4)	6.53 *	0.01061 *	5.76 (1.27–26.09) *
	CT + TT	71 (26.6)	149 (42.2)	16.2 *	0.00006 *	2.02 (1.43–2.84) *
	allele frequency
	C	461 (86.33)	545 (77.2)			Ref.
	T	73 (13.67)	161 (22.8)	16.57 *	0.00006 *	1.87 (1.38–2.53) *
S. Saravani et al. (2017) [40]	+279 A/G (rs17576)	Σn = 120	Σn = 120
	genotype
	GG	102 (85)	84 (70)			Ref.
	AG	18 (15)	36 (30)	7.74 *	0.00540*	2.43 (1.29–4.58) *
	AA	0	0		1.00000
	allele frequency
	G	222 (92.5)	204 (85)			Ref.
	A	18 (7.5)	36(15)	6.76 *	0.00932 *	2.18 (1.2–3.95) *

* Values calculated based on the data presented by the authors.