Skip to main content
. 2022 Sep 6;14(9):1886. doi: 10.3390/pharmaceutics14091886

Figure 3.

Figure 3

Schematic representation of the sonication method for the SLN probe sonicator (A), bath sonicator used in academic labs (B) and SLN preparation by the sonication method (C). In this technique, the lipids will be melted and the aqueous phase with surfactants is then sonicated using probe sonicator to form emulsions with reduced droplet size. Gradual cooling of the emulsion below the crystallization temperature helps in formation of the SLN dispersions. Note: (A,B) figures are adapted with permission from Ref. [23]. Copyright 2014, Elsevier, and (C) is adapted from Ref. [24].