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. 2022 Sep 12;27(18):5928. doi: 10.3390/molecules27185928

Figure 2.

Figure 2

Structures of D-mannose, D-glucose, 2-DG (2-deoxy-D-glucose; 2-deoxy-D-mannose), and WP1122 (2-DG prodrug). Within the cell, WP1122 is deacetylated by cellular esterases to monoacetates: WP1124 and WP1125, and subsequently release active 2-DG.