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. 2022 Sep 9;27(18):5848. doi: 10.3390/molecules27185848

Figure 9.

Figure 9

Results of plasma coagulation assays. Effect of the cationic antimicrobial peptides (CAMPs) pept_1, pept_2, pept_3, pept_4, pept_5, pept_6, pept_7 and pept_8 on activated partial thromboplastin time (APTT, (A)) and prothrombin time (PT, (B)). The coagulation kit’s normal pooled plasma was used. Before assaying for coagulation, plasma samples were pre-incubated with or without peptides for 15 min at room temperature. In each group of bars, from left to right: 25 μM, 50 μM, and 100 μM peptide concentrations in pre-incubated plasma. Plasma without peptides served as control, which was set to 100%. Data shown are mean ± SD from three independent experiments, with duplicate samples in each experiment. * p < 0.05 compared to control plasma.