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. 2022 Sep 16;23(18):10794. doi: 10.3390/ijms231810794

Figure 6.

Figure 6

The possible antibiotic mechanism of penicillin. The peptidoglycan contains temporary D-alanyl-D-ala groups during crosslinking processes. Crosslink would be terminated while D-alanyl-D-ala was replaced by penicillin. The glycan strands consist of alternating N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc). The crosslinking of glycan strands is through the connection of meso-diaminopimelic acid (meso-Dap) and D-Ala.