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. 2022 Sep 16;15(9):1156. doi: 10.3390/ph15091156

Table 3.

Absorption prediction of A. halimus leaf ethanolic extract.

Water Solubility Caco-2 Permeability Intestinal Absorption Skin Permeability P-gp Substrate P-gp I Inhibitor P-gp II Inhibitor
Units Log mol/L Log Papp in 10−6 cm/s % cm/s Categorical (Yes/No)
Gallic acid −1.64 −0.08 43.37 −2.73 No No No
Syringic acid −1.84 0.49 73.07 −2.73 No No No
Trans-ferulic acid −2.11 0.17 93.68 −2.72 No No No
Myricetin −3.01 0.09 65.93 −2.73 No No No
Catechin gallate −3.70 −1.26 62.09 −2.73 No No Yes
Caffeic acid −1.89 0.63 69.40 −2.72 No No No
Chlorogenic acid −1.62 −0.84 36.37 −2.73 No No No
Arbutin −0.71 0.00 38.02 −2.80 No No No
Trimethoxyflavone −4.11 1.40 98.07 −2.57 No Yes Yes