Table 1.

CD markers on dendritic cell subtypes. Breakdown of DC populations by location including lymph nodes, spleen, thymus, blood, skin, and gut. Differential CD expression among this population of cells. The table also notes proliferative factors for select DC subtypes.

DC Location	CD Molecule Expression	Cytokines and Signaling Molecules
Lymph Nodes	CD80, CD86, CD40	CCR7, CCL19/CCL21, CXCL9/10,
Spleen	CD8, Esam(hi)CD11b+, CD205, CD207, Clec9a	Proliferate in presence of Flt3L, Notch2
Thymus	CD8, CD8a, CD207, CD1a, CD11c	SIRPα+ dependent on CCR2 chemotaxis, S100,
Blood (pDC, cDC, iDC)	pDC: BDCA2, BDCA4 cDC: CD11	CCR7, CCR2, CXCR3, MHCI, IL-12, IL-2, IL-15, CCL3, CXCL8, TNF
Skin (Langerhans)	CD207, CD45, CD11c, CD1a, CD14, CD141	Proliferate independent of Flt3; Dependent on CSF-1R which induces chemokines CCL2 & CCL20, CCR7, CCL21, CCR2, IFN-λ, TLR3, IFN-α/β, IL-12p40, XCR1, IDO, TLR2/8, CD5, TLR7
Gut	CD8, CD103, CD207, CD11b, CD70	Proliferate in presence of Flt3L, Notch2, ALDH1A1/2, RA, IL-5, IL-6, TGFβ, CX3CR1, TLR5, Flagellin, TSLP, IL-23