Table 1.
Serum BDG values, overall sensitivity, and sensitivity stratified according to Candida species.
| Candida Species (Total Number of Episodes = 146; Total Number of BDG Samples = 187) § | Median BDG Value (IQR), in pg/mL §§ | Median Time from Candidemia Onset to First BDG Determination (IQR), in Days | Sensitivity (95% CI) |
|---|---|---|---|
| For all samples (n = 187) | 84 (21–314) | −0.06 (−1.28, 0.83) | 51.3% (44.1–58.5%) |
| For all episodes (n = 146) | 47.3% (39.0–55.0%) | ||
| For C. albicans (n = 40) samples | 182 (30.5–523) | 0 (−1.16–0.78) | 65.0% (48.7–78.4%) |
| For C. albicans (n = 29) episodes | 62.1% (42.8–78.2%) | ||
| For C. parapsilosis (n = 105) samples | 78 (19–290) | −0.08 (−1.29–1.00) | 48.6% (39.1–58.2%) |
| For C. parapsilosis (n = 84) episodes | 44.0% (33.7–54.9%) | ||
| For C. auris (n = 26) samples | 48 (15–159) | 0 (−1.99–0.83) | 42.3% (24.5–62.4%) |
| For C. auris (n = 21) episodes | 42.9% (23.0–65.3%) | ||
| For other species (n = 16) samples * | 81 (29–195) | −0.62 (−1.99–0.53) | 50.0% (25.6–74.4%) |
| For other species (n = 12) episodes ** | 41.7% (16.4–72.2%) |
§ Number of episodes refers to the number of candidemia episodes; §§ Referred to total number of BDG samples; * C. glabrata n = 11, C. tropicalis n = 4, C. lusitaniae n = 1; ** C. glabrata n = 7, C. tropicalis n = 4, C. lusitaniae n = 1; BDG: b-D-glucan, 95% CI: 95% confidence interval; IQR: interquartile range.